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A skin biopsy for the measurement of epidermal nerve fiber density is an increasingly common technique for the diagnosis of small fiber peripheral neuropathy. [13] Physicians can biopsy the skin with a 3-mm circular punch tool and immediately fix the specimen in 2% paraformaldehyde lysine-periodate or Zamboni's fixative. [ 20 ]
Cutaneous innervation of the lower limbs is the nerve supply to areas of the skin of the lower limbs (including the feet) which are supplied by specific cutaneous nerves. Modern texts are in agreement about which areas of the skin are served by which nerves , but there are minor variations in some of the details.
The peripheral nervous system (PNS) is divided into the somatic nervous system, the autonomic nervous system, and the enteric nervous system.However, it is the somatic nervous system, responsible for body movement and the reception of external stimuli, which allows one to understand how cutaneous innervation is made possible by the action of specific sensory fibers located on the skin, as well ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Posterior ramus syndrome, also referred to as thoracolumbar junction syndrome, Maigne syndrome and dorsal ramus syndrome is caused by the unexplained activation of the primary division of a posterior ramus of a spinal nerve (dorsal ramus of spinal nerve). This nerve irritation causes referred pain in a well described tri-branched pattern. The ...
The medial sural cutaneous nerve originates from the posterior aspect of the tibial nerve of the sciatic nerve. [2] [3] It descends between the two heads of the gastrocnemius muscle. [2] [3] Around the middle of the back of the leg, it pierces the deep fascia to become superficial. [3] It unites with the lateral sural cutaneous nerve to form ...