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Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]
It produces melatonin, a serotonin-derived hormone, which modulates sleep patterns following the diurnal cycles. [2] The shape of the gland resembles a pine cone , which gives it its name. [ 3 ] The pineal gland is located in the epithalamus , near the center of the brain, between the two hemispheres , tucked in a groove where the two halves of ...
One expert says the sleep aid is "overused" by some families.
Further, melatonin functions as a neuroprotective, pain-reducer, tumor suppressor, reproduction stimulant, and antioxidant. [5] Melatonin has an anti-excitatory effect on brain activity which is exemplified by its reduction of epileptic activity in children which is to say that it is an inhibitory transmitter. [5]
Melatonin. Melatonin is naturally produced in the brain. Melatonin is naturally produced in the brain. The hormone rises at bedtime, peaks in the middle of the night, and then decreases until it ...