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Laboratory animal suppliers in the United Kingdom breed animals such as rodents, rabbits, dogs, cats and primates which they sell to licensed establishments for scientific experimentation. Many have found themselves at the centre of animal rights protests against animal testing .
Animal testing regulations are guidelines that permit and control the use of non-human animals for scientific experimentation.They vary greatly around the world, but most governments aim to control the number of times individual animals may be used; the overall numbers used; and the degree of pain that may be inflicted without anesthetic.
Animal testing is widely used to aid in research of human disease when human experimentation would be unfeasible or unethical. [26] This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. [27]
Prior to ASPA, the use of animals in the UK was regulated by the Cruelty to Animals Act 1876, which enforced a licensing and inspection system for vivisection.Animal cruelty was previously regulated by the Protection of Animals Act 1911 (now largely repealed) and more recently by the Animal Welfare Act 2006, both of which outlaw the causing of "unnecessary suffering".
Exclusive: One in three researchers say their peers force them to carry out tests with animals if their work is to be published, while others are too scared to speak out
Transgenic animal production consists of injecting each construct into 300–350 eggs, typically representing three days' work. Twenty to fifty mice will normally be born from this number of injected eggs. These animals are screened for the presence of the transgene by a polymerase chain reaction genotyping assay. The number of transgenic ...
One of Pavlov’s dogs with a saliva-catch container and tube surgically implanted in its muzzle, Pavlov Museum, 2005. The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. [1]
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