Ad
related to: difference between embryo and oocyte cancer symptoms mayo clinic
Search results
Results From The WOW.Com Content Network
Ovarian cancer's early stages (I/II) are difficult to diagnose because most symptoms are nonspecific and thus of little use in diagnosis; as a result, it is rarely diagnosed until it spreads and advances to later stages (III/IV). [58] Additionally, symptoms of ovarian cancer may appear similar to irritable bowel syndrome.
Common symptoms of OGCT are bloating, abdominal distention, ascites, and dyspareunia. [1] OGCT is caused mainly due to the formation of malignant cancer cells in the primordial germ cells of the ovary. [1] The exact pathogenesis of OGCTs is still unknown however, various genetic mutations and environmental factors have been identified. [1]
Autoimmune disorders can lead to complications in implantation of the egg in the uterus, which may be the immune system's attack response to an established embryo on the uterine wall. [36] Cancer ultimately affects fertility and may lead to birth defects or miscarriages. Cancer severely damages reproductive organs, which affects fertility. [36]
Oocytes are then able to mature within the follicle through meiosis. In humans with ovaries, this process occurs continuously, as they are born with a finite number of follicles (between 500,000-1,000,000 follicles), and about 99% of follicles undergo atresia. [4] Only one follicle will be mature enough to release an egg and may be fertilized. [5]
Ovulation is triggered by a spike in the amount of FSH and LH released from the pituitary gland. During the luteal (post-ovulatory) phase, the secondary oocyte will travel through the fallopian tubes toward the uterus. If fertilized by a sperm, the fertilized secondary oocyte or ovum may implant there 6–12 days later. [11]
Women diagnosed with cancer who have not yet begun chemotherapy or radiotherapy can benefit from Oocyte cryopreservation. [3] Chemotherapy and radiotherapy are toxic to oocytes, reducing the number of viable eggs. Egg-freezing may be used in this case to preserve eggs as opposed to Oocyte cryopreservation. [clarification needed] [citation needed]
Oocyte abnormalities can be caused by a variety of genetic factors affecting different stages in meiosis. [1] Moreover, ageing is associated with oocyte abnormalities since higher maternal age is associated with oocytes with a reduced gene expression of spindle assembly checkpoints which are important in maintaining stability in the genome.
An oocyte (/ ˈ oʊ ə s aɪ t /, oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis ...