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The Dutch, British and French system called the System of Objectified Judgement Analysis for assessing whether drugs should be included in drug formularies based on clinical efficacy, adverse effects, pharmacokinetic properties, toxicity, and drug interactions was used to assess nitrazepam. A Dutch analysis using the system found nitrazepam to ...
Most side effects are direct consequences of the vasodilation and the resultant low blood pressure. They include headache ("nitrate headache") resulting from the widening of blood vessels in the brain, reflex tachycardia (fast heart rate), flush, dizziness, nausea and vomiting. These effects usually subside after a few days if the treatment is ...
Serious side effects may include low blood pressure especially if also exposed to PDE5 inhibitors such as sildenafil. [2] Use is not recommended in pregnancy. [3] It is believed to work by relaxing smooth muscle within blood vessels. [2] It was patented in 1971 and approved for medical use in 1981. [4] It is available as a generic medication. [3]
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
Nitrates affect the nitrate‐nitrite‐nitric oxide pathway, ... is a newer ED medication that’s fast-acting and less likely to cause certain side effects than older medications.
Nitrates affect a process called the nitrate‐nitrite‐nitric oxide ... avanafil is a newer ED medication that’s fast-acting and less likely to cause certain side effects than older medications.
Many of the severe side effects of this drug are more common in the elderly and those with renal impairment, as this causes the drug to be retained in the body and reach higher systemic levels. Thus, the drug is not recommended for the elderly population according to 2012 AGS Beers Criteria. [43]
Nitrates affect a process called the nitrate‐nitrite‐nitric oxide ... avanafil is a newer ED medication that’s fast-acting and less likely to cause certain side effects than older medications.