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Peginterferon alfa-2a is a long acting interferon. Interferons are proteins released in the body in response to viral infections . Interferons are important for fighting viruses in the body, for regulating reproduction of cells , and for regulating the immune system.
Pegylated interferon alfa-2b is a drug used to treat melanoma, as an adjuvant therapy to surgery. [3] Also used to treat hepatitis C (typically, in combination with ribavarin), it is no longer recommended due to poor efficacy and adverse side-effects. [4]
Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: [1]. Pegylated interferon-alpha-2a; Pegylated interferon-alpha-2b ...
INCIVEK ® (telaprevir) should always be used in combination with peginterferon alfa and ribavirin. INCIVEK combination treatment may cause serious side effects including skin rash and serious ...
Based on the type of receptor through which they signal, human interferons have been classified into three major types.. Interferon type I: All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α/β receptor that consists of IFNAR1 and IFNAR2 chains. [5]
Peginterferon beta-1a, sold under the brand name Plegridy, is medication used to treat multiple sclerosis. [ 4 ] [ 5 ] The most common side effects include headache, muscle pain, joint pain, influenza (flu)-like symptoms, pyrexia (fever), chills, asthenia (weakness), and erythema (reddening of the skin), pain or pruritus (itching) at the ...
Peginterferon-alfa may refer to: Peginterferon alfa-2a, an antiviral drug used in treatment for hepatitis C and hepatitis B; Peginterferon alfa-2b, a treatment for ...
For HCV, it is used in combination with other medications, such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a. [1] It can also be used for viral hemorrhagic fevers—specifically, for Lassa fever, Crimean–Congo hemorrhagic fever, and Hantavirus infections (with exceptions for Ebola or Marburg virus diseases). [1]
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