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  2. Hypothyroidism in dogs - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism_in_dogs

    Hypothyroidism is classified as either primary, secondary, or tertiary. Primary hypothyroidism is for when the cause is due to an abnormality of the thyroid gland, secondary hypothyroidism is when the cause is decreased thyroid-stimulating hormone levels, and tertiary hypothyroidism is when the cause is an inadequate amount of thyrotropin-releasing hormone being released.

  3. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland. The hypothalamus senses low circulating levels of thyroid hormone (Triiodothyronine (T3) and Thyroxine (T4)) and responds by releasing thyrotropin-releasing hormone (TRH). The TRH stimulates the anterior pituitary to produce thyroid-stimulating ...

  4. Thyroxine - Wikipedia

    en.wikipedia.org/wiki/Thyroxine

    It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1] Thyroxine and its active metabolites are essential for regulating metabolic rate , supporting heart and muscle function , promoting brain development , and maintaining bone health .

  5. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    Thyroid hormones act on nearly every cell in the body. They act to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neural maturation, and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. [12]

  6. Hypersomatotropism (veterinary) - Wikipedia

    en.wikipedia.org/wiki/Hypersomatotropism...

    Dogs with primary hypothyroidism also have increased levels of growth hormone and IGF-1; however, thyroxine and thyroid stimulating hormone levels are normal in dogs with hypersomatotropism. [1] Progestogens administered to dogs may result in endogenous adrenocorticotropic hormone secretion being suppressed, which lowers the cortisol ...

  7. A dog's life: study reveals people's hormonal link with tail ...

    www.aol.com/news/2015-04-17-a-dogs-life-study...

    People whose dogs had the most eye contact with them - a mutual gaze - registered the largest increases in oxytocin levels. The dogs also had an oxytocin spike correlating with that of their owner.

  8. Organification - Wikipedia

    en.wikipedia.org/wiki/Organification

    Organification is a biochemical process that takes place in the thyroid gland. It is the incorporation of iodine into thyroglobulin for the production of thyroid hormone, a step done after the oxidation of iodide by the enzyme thyroid peroxidase (TPO) [1] Since iodine is an inorganic compound, and is being attached to thyroglobulin, a protein, the process is termed as "organification of iodine".

  9. Thyroid hormone receptor - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormone_receptor

    TSH stimulates the thyroid to secrete thyroid hormone. Once secreted, thyroid hormone acts on these receptors and inhibits transcription of Tshb. This feedback inhibition stops further TSH production, inhibiting thyroid hormone secretion downstream. When the THRB gene is mutated, the receptors on the pituitary can no longer bind thyroid hormone.