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In medicine, tapering is the practice of gradually reducing the dosage of a medication to reduce or discontinue it. Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug.
In a comparison study, a rapid taper using benzodiazepines was found to be superior to a phenobarbital rapid taper. [106] [107] Pregabalin may help reduce the severity of benzodiazepine withdrawal symptoms, [108] and reduce the risk of relapse. [109] Propranolol was not found to increase the discontinuation success rate. [86]
With careful physician attention, however, medication prioritization and discontinuation can decrease costs, simplify prescription regimens, decrease risks of adverse drug events and poly-pharmacy, focus therapies where they are most effective, and prevent cost-related under-use of medications.
The Independent on Sunday reported allegations that "scores" of the 1.5 million members of the UK public who use benzodiazepines long-term have symptoms that are consistent with brain damage. It has been described as a "huge scandal" by Jim Dobbin , and legal experts and MPs have predicted a class action lawsuit.
New research suggests that slowly tapering off GLP-1 drugs like Ozempic and Wegovy while adopting lifestyle changes may help prevent rebound weight gain. ... regain if they go off their medication ...
A former TD Bank employee based in Florida was arrested and charged with facilitating money laundering to Colombia, New Jersey's attorney general said on Wednesday, in the first such arrest since ...
Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.
He had tried it on the black market to stave off sickness when he couldn’t get heroin — what law enforcement calls diversion. But Patrick had just left a facility that pushed other solutions. He had gotten a crash course on the tenets of 12-step, the kind of sped-up program that some treatment advocates dismissively refer to as a “30-day ...