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Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic ; if symptoms appear, they typically begin 3 to 14 days after infection.
dengue fever; malaria; tuberculosis. NITD's research model relies on global partnership with other research institutes. [1] In 2008, NITD announced a 5-year collaborative research effort would be conducted in cooperation with the TB Alliance to develop new medicines for tuberculosis, including drug resistant tuberculosis. [5]
Dengue fever (UK: / ˈ d ɛ ŋ ɡ eɪ / or US: / ˈ d ɛ ŋ ɡ iː /), also known as breakbone fever, is an infectious tropical disease caused by the dengue virus. Symptoms include fever , headache , myalgias and arthralgias , and a characteristic skin rash that is similar to measles .
65,758 cases of dengue fever have been reported up to EW 19 in Mexico, accounting for 0.8% of total cases in Latin America and the Caribbean in 2024. 405 severe cases and 20 deaths have been reported so far in Mexico, with a fatality rate of 0.03%. DENV1, DENV2, DENV3 and DENV4 serotypes have been detected in Mexico. [3]
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
However around 10% of those 800,000 had not had dengue fever before and therefore are at risk of severe infection because of the vaccine. [ 2 ] In the Philippines, the Dengvaxia controversy has contributed to overall vaccine hesitancy because of heightened concerns about vaccine safety.