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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
The cell membranes may then be damaged if the horse is forced to continue work, which allows muscle enzymes and myoglobin to leak into the bloodstream. [1] This leads to the body building up a store of glycogen from converted carbohydrates in muscle cells. Glycogen is then depleted during work, and restocked when a horse rests.
Chlorpromazine may be used as an antiemetic in dogs and cats, or, less often, as a sedative before anesthesia. [73] In horses, it often causes ataxia and lethargy and is therefore seldom used. [72] [73] It is commonly used to decrease nausea in animals that are too young for other common antiemetics.
The FDA has not officially approved the use of Apoquel in cats. However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study.
The size of a race horse and its natural instincts make it nearly impossible to survive serious injuries at the track, but many are trying to improve the odds. Why do race horses keep dying?
Many horse management handbooks recommend grooming a horse daily, though for the average modern horse owner, this is not always possible. However, a horse should always be groomed before being ridden to avoid chafing and rubbing of dirt and other material, which can cause sores on the animal and also grind dirt into horse tack .
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The early history of horse doping is unclear, although according to Euripides (480-406 BC), some horses were fed human flesh to make them faster and more savage. However, during Roman times, the use of hydromel for chariot race horses was punished by crucifixion.