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Coronary heart disease (CHD) risk at 10 years in percent can be calculated with the help of the Framingham Risk Score. Individuals with low risk have 10% or less CHD risk at 10 years, with intermediate risk 10-20%, and with high risk 20% or more. However, it should be remembered that these categorisations are arbitrary. [citation needed]
Also, there are risk assessment tools for estimating the combined risk of several risk factors, such as the online tool from the Framingham Heart Study for estimating the risk for coronary heart disease outcomes using multiple risk factors, including age, gender, blood lipids, blood pressure and smoking, being much more accurate than ...
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.
Tobacco smoking is a clear risk factor for development of coronary artery disease. [13] Exposure to second hand smoke also has clear cardiovascular risks. [13] Tobacco smokers have higher levels of cholesterol and triglycerides which are risk factors for development of coronary artery disease. [40]
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
Specific to public health policy, a determinant is a health risk that is general, abstract, related to inequalities, and difficult for an individual to control. [2] [3] [4] For example, poverty is known to be a determinant of an individual's standard of health. Risk factors may be used to identify high-risk people.
Which conditions are risk factors for MACE depends on some characteristics of the investigated cohort. Established risk indicators in the general population include age, pre-existing cardiovascular disease, smoking, diabetes mellitus, elevated concentrations of triglycerides and non-HDL cholesterol concentration, reduced HDL concentration and hypertension, as, e. g., demonstrated by the ...