Ad
related to: organophosphate insecticides examples list of medications
Search results
Results From The WOW.Com Content Network
Pages in category "Organophosphate insecticides" The following 68 pages are in this category, out of 68 total. This list may not reflect recent changes. A.
Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [ 32 ] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects.
A variety of mixed amido-alkoxo derivatives are known, one medically significant example being the anti-cancer drug cyclophosphamide. Also derivatives containing the thiophosphoryl group (P=S) include the pesticide malathion. The organophosphates prepared on the largest scale are the zinc dithiophosphates, as additives for motor oil.
These compounds are the basis of antisense therapy, e.g., the drugs fomivirsen (Vitravene), oblimersen, alicaforsen, and mipomersen (Kynamro). [2] Further examples of these include: Diazinon; Fenitrothion; Fenthion; Thiotepa; Variants with P=S double bonds were developed as insecticides because of their reduced mammalian toxicity.
Organophosphate insecticides (68 P) Organophosphate nerve agents (3 C, 5 P) Organophosphorohalidates (1 C, 1 P) Organophosphoropseudohalidates (1 P) P. Phospholipids ...
Organophosphate insecticides and chemical warfare nerve agents (such as sarin, tabun, soman, and VX) have the same mechanism of action. Organophosphates have a cumulative toxic effect to wildlife, so multiple exposures to the chemicals amplifies the toxicity. [19] In the US, organophosphate use declined with the rise of substitutes. [20]
Malathion is a pesticide that is widely used in agriculture, residential landscaping, public recreation areas, and in public health pest control programs such as mosquito eradication. [5] In the US, it is the most commonly used organophosphate insecticide.
Dimethoate is a widely used organophosphate insecticide and acaricide. It was patented and introduced in the 1950s by American Cyanamid. Like other organophosphates, dimethoate is an acetylcholinesterase inhibitor which disables cholinesterase, an enzyme essential for central nervous system function. It acts both by contact and through ingestion.