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  2. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/lifestyle/switching-antidepressants...

    When switching antidepressants, your healthcare provider may recommend switching directly, cross-tapering or tapering down your dosage before you start using your new medication.

  3. Is It Time to Switch from Zoloft to Prozac? How to Tell

    www.aol.com/lifestyle/switching-zoloft-prozac...

    Home & Garden. Lighter Side

  4. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    In adults and children with bipolar disorder, SSRIs may cause a bipolar switch from depression into hypomania/mania, mixed states or rapid cycling. [159] When taken with mood stabilizers , the risk of switching is not increased, however when taking SSRIs as a monotherapy , the risk of switching may be twice or three times that of the average.

  5. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Approximately 15–50% of people who suddenly stop an antidepressant develop antidepressant discontinuation syndrome. [7] [2] [3] [4] The condition is generally not serious, [2] though about half of people with symptoms describe them as severe. [4] Many restart antidepressants due to the severity of the symptoms. [4]

  6. Bipolar II disorder - Wikipedia

    en.wikipedia.org/wiki/Bipolar_II_disorder

    Thus, in most cases, antidepressant monotherapy in patients with BP-II is not recommended. However, antidepressants may provide benefit to some patients when used in addition to mood stabilizers and antipsychotics, as these drugs reduce the risk of manic/hypomanic switching. [40] However, the risk still exists, and should be used with caution. [35]

  7. STAR*D - Wikipedia

    en.wikipedia.org/wiki/STAR*D

    Among the patients who were switched to a different antidepressant, there was no significant difference among the different antidepressants. For level three, the remission rates based on the HAM-D symptom scale were 12.3% for mirtazapine and 19.8% for nortriptyline, although the difference was not large enough for statistical significance. [5]

  8. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    Ketamine’s antidepressant effects are part of what prompted researchers to explore other drugs that target glutamate—like the venerable cough suppressant dextromethorphan found in Robitussin ...

  9. Nortriptyline - Wikipedia

    en.wikipedia.org/wiki/Nortriptyline

    A level between 50 and 150 ng/mL of nortriptyline in the blood generally corresponds with an antidepressant effect. [12] It is also used off-label for the treatment of panic disorder, ADHD, irritable bowel syndrome, tobacco-cessation, migraine prophylaxis and chronic pain or neuralgia modification, particularly temporomandibular joint disorder.