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Doxycycline has not been widely studied as a treatment in the US, but antibiotic sensitivities of prevailing European and US isolates of Borrelia burgdorferi tend to be identical. However, doxycycline is generally not prescribed to children due to the risk of bone and tooth damage. [7] Discredited treatments for neuroborreliosis include:
Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. [ 1 ] [ 2 ] Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato .
Treatment: Antibiotics – amoxicillin in pregnant adults and children, doxycycline in other adults [30] Relapsing fever (tick-borne relapsing fever, different from Lyme disease due to different Borrelia species and ticks) Organisms: Borrelia species such as B. hermsii, B. parkeri, B. duttoni, B. miyamotoi; Vector: Ornithodoros species
[3] [4] Borrelia species in the species complex known to cause Lyme disease are collectively called Borrelia burgdorferi sensu lato (s.l.), not to be confused with the single species Borrelia burgdorferi sensu stricto, a member of the complex, which is responsible for nearly all cases of Lyme disease in North America. [5]
Borrelia miyamotoi is a bacterium of the spirochete phylum in the genus Borrelia. A zoonotic organism, B. miyamotoi can infect humans through the bite of several species of hard-shell Ixodes ticks, the same kind of ticks that spread B. burgdorferi , the causative bacterium of Lyme disease .
Bright light therapy is a treatment method that involves exposure to a high-intensity light source that mimics natural sunlight, says Frank A. Ghinassi, Ph.D., senior vice president of Behavioral ...
Mitomycin C has been shown to have activity against stationary phase persisters caused by Borrelia burgdorferi, a factor in lyme disease. [ 7 ] [ 8 ] Mitomycin C is used to treat pancreatic and stomach cancer , [ 9 ] and is under clinical research for its potential to treat gastrointestinal strictures , [ 10 ] wound healing from glaucoma ...