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Once the horse returns to work and/or exercise, the glycogen can rapidly form to usable energy. If there is too much of it, this can cause an imbalance, which can form into Sporadic ER. [1] The excess glycogen within the muscle cells that lack oxygen begin to function anaerobically to produce the needed Adenosine Triphosphate. The anaerobic ...
Equine polysaccharide storage myopathy (EPSM, PSSM, EPSSM) is a hereditary glycogen storage disease of horses that causes exertional rhabdomyolysis.It is currently known to affect the following breeds American Quarter Horses, American Paint Horses, Warmbloods, Cobs, Dales Ponies, Thoroughbreds, Arabians, New Forest ponies, and a large number of Heavy horse breeds.
The same phenomenon may happen in conditions that lead to hemolysis, the destruction of red blood cells; in hemolysis the blood serum is also visibly discolored, while in rhabdomyolysis it is normal. [ 13 ] [ 18 ] If kidney damage has occurred, microscopy of the urine also reveals urinary casts that appear pigmented and granular.
It has been shown to be detrimental to the viability of skin grafts in horses, [114] and only minimal effects on horses with induced endotoxemia. [115] HBOT is considered very safe, with few contraindications, although its cost and availability make it less widely used than most other forms of treatment.
Side effects are not common, but the use of acepromazine in stallions should be used with caution (but is not absolutely contraindicated) due to the risk of paraphimosis and priapism. [ 6 ] Acepromazine also lowers blood pressure, and should therefore be used with caution in horses that are experiencing anemia , dehydration , shock , or colic .
Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.
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