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In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. [2] Low levels of platelets in turn may lead to prolonged or excessive bleeding.
Glanzmann's thrombasthenia can be inherited in an autosomal recessive manner [3] [4] or acquired as an autoimmune disorder. [3] [5]The bleeding tendency in Glanzmann's thrombasthenia is variable, [3] some individuals having minimal bruising, while others have frequent, severe, potentially fatal hemorrhages.
Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding. Giant platelets cannot stick adequately to injured blood vessel walls, resulting in abnormal bleeding when injured.
Clinical data show that many patients with serious bacterial or viral infections have thrombocytopenia, thus reducing their contribution to inflammation. Platelet-leukocyte aggregates (PLAs) found in circulation are typical in sepsis or inflammatory bowel disease , showing the connection between thrombocytes and immune cells.
Thrombosis (from Ancient Greek θρόμβωσις (thrómbōsis) ' clotting ') is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
A region of interest (often abbreviated ROI) is a sample within a data set identified for a particular purpose. [1] The concept of a ROI is commonly used in many application areas. Existing as a vicinity, or within one.
When drawing data from a sample, this means that the rejection region comprises 5% of the sampling distribution. [39] These 5% can be allocated to one side of the sampling distribution, as in a one-tailed test , or partitioned to both sides of the distribution, as in a two-tailed test , with each tail (or rejection region) containing 2.5% of ...
Encyclopædia Britannica, a printed encyclopedia, and Wikipedia, an online encyclopedia. An encyclopedia [a] is a reference work or compendium providing summaries of knowledge, either general or special, in a particular field or discipline.