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In physiology, thermoception or thermoreception is the sensation and perception of temperature, or more accurately, temperature differences inferred from heat flux.It deals with a series of events and processes required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal in order to trigger an appropriate defense response.
Arterioles carrying blood to superficial capillaries under the surface of the skin can shrink (constrict), thereby rerouting blood away from the skin and towards the warmer core of the body. This prevents blood from losing heat to the surroundings and also prevents the core temperature dropping further. This process is called vasoconstriction.
This results in a net movement of positive charge out of the cell, i.e. a hyperpolarizing current. The magnitude of this current is proportional to the rate of pump activity. It has been suggested that it is the constellation of various thermally sensitive proteins together in a neuron that gives rise to a cold receptor. [6]
A glomus body (or glomus organ; plural glomera) is a component of the dermis layer of the skin, involved in body temperature regulation. [1] [2] The glomus body is a small arteriovenous anastomosis surrounded by a capsule of connective tissue. Glomera are most numerous in the fingers and toes.
Cutaneous receptors are at the ends of afferent neurons. works within the capsule. Ion channels are situated near these networks. In sensory transduction, the afferent nerves transmit through a series of synapses in the central nervous system, first in the spinal cord, the ventrobasal portion of the thalamus, and then on to the somatosensory cortex.
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature as its own body temperature, thus avoiding the need for internal thermoregulation.
Often expressed in cm/s. This value is inversely related to the total cross-sectional area of the blood vessel and also differs per cross-section, because in normal condition the blood flow has laminar characteristics. For this reason, the blood flow velocity is the fastest in the middle of the vessel and slowest at the vessel wall.
Paracrine signaling occurs between nearby cells. Endocrine interaction occurs between distant cells, with the chemical signal usually carried by the blood. [4] Receptors are complex proteins or tightly bound multimer of proteins, located in the plasma membrane or within the interior of the cell such as in the cytoplasm, organelles, and nucleus ...