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Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, [1] resulting in the formation of peroxide and hydroperoxide derivatives. [2] It occurs when free radicals , specifically reactive oxygen species (ROS), interact with lipids within cell membranes , typically polyunsaturated fatty ...
Another method of termination is the reaction between a lipid radical and a lipid peroxide, or the combination of two lipid peroxide molecules, resulting in stable nonreactive molecules. [ 4 ] [ 5 ] Reinforced lipids that become part of the membrane if consumed with heavy isotope diet also inhibit peroxidation.
It emphasizes whole, unprocessed foods like fresh fruits and vegetables, whole grains, legumes, nuts, and seeds, along with healthy fats from sources like olive oil and fatty fish.
Phosphatidylethanolamines in food break down to form phosphatidylethanolamine-linked Amadori products as a part of the Maillard reaction. [13] These products accelerate membrane lipid peroxidation, causing oxidative stress to cells that come in contact with them. [14] Oxidative stress is known to cause food deterioration and several diseases.
Eating walnuts, in particular, can help reduce blood pressure, decrease inflammation and lower LDL (low-density lipoprotein, the “bad” cholesterol) and total cholesterol levels. Almonds Cashews
This probably is an indication of the greater vulnerability of polyunsaturated fats to lipid peroxidation, against which vitamin E has been shown to be protective. [ 5 ] Examples of unsaturated fatty acids are palmitoleic acid , oleic acid , myristoleic acid , linoleic acid , and arachidonic acid .
It has been claimed [by whom?] that the α-tocopherol form is the most important lipid-soluble antioxidant, and that it protects membranes from oxidation by reacting with lipid radicals produced in the lipid peroxidation chain reaction. [82] [85] This removes the free radical intermediates and prevents the propagation reaction from continuing.
In a 2019 study, probiotic yogurt was found to significantly reduce total and LDL cholesterol in adults with mild to moderately high cholesterol. Photographer, Basak Gurbuz Derman - Getty Images Water