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The constant communication between the heart and the brain have proved invaluable to the interdisciplinary fields of neurological and cardiac diseases. [4] The fundamental understanding of the communication between the heart and the brain via the nervous system has led scientists towards an understanding of its elaborate circuitry.
The "little brain in the heart" is an intricate system of nerve cells that control and regulate the heart's activity. It is also called the intrinsic cardiac nervous system (ICNS). [15] It consists of about 40,000 neurons that form clusters or ganglia around the heart, especially near the top where the blood vessels enter and exit.
Brain cells make up the functional tissue of the brain. The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges , blood vessels , and ducts. The two main types of cells in the brain are neurons , also known as nerve cells, and glial cells , also known as neuroglia. [ 1 ]
Brain organoids, which are structures derived from stem cells, are used to study brains. Now with 3D printing, this method allows scientists to have more flexibility in their studies.
These form the ventricular system of the brain: [8] The neural stem cells of the developing brain, principally radial glial cells, line the developing ventricular system in a transient zone called the ventricular zone. [9] The prosencephalon divides into the telencephalon, which forms the cortex of the developed brain, and the diencephalon.
In brain tissue, a biochemical cascade known as the ischemic cascade is triggered when the tissue becomes ischemic, potentially resulting in damage to and the death of brain cells. Medical professionals must take steps to maintain proper CBF in patients who have conditions like shock , stroke , cerebral edema , and traumatic brain injury .
Various cell types play a role in HR, including astrocytes, smooth muscle cells, endothelial cells of blood vessels, and pericytes. These cells control whether the vessels are constricted or dilated, which dictates the amount of oxygen and glucose that is able to reach the neuronal tissue. Brain blood vasculature as a function of blood flow.
The neural crest runs the length of the tube with cranial neural crest cells at the cephalic end and caudal neural crest cells at the tail. Cells detach from the crest and migrate in a craniocaudal (head to tail) wave inside the tube. [67] Cells at the cephalic end give rise to the brain, and cells at the caudal end give rise to the spinal cord ...