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MRI contrast agents may be administered by injection into the blood stream or orally, depending on the subject of interest. Oral administration is well suited to gastrointestinal tract scans, while intravascular administration proves more useful for most other scans. MRI contrast agents can be classified [2] by their: Chemical composition
The first study of the human brain at 3.0 T was published in 1994, [13] and in 1998 at 8 T. [14] Studies of the human brain have been performed at 9.4 T (2006) [15] and up to 10.5 T (2019). [16] Paul Lauterbur and Sir Peter Mansfield were awarded the 2003 Nobel Prize in Physiology or Medicine for their discoveries concerning MRI.
MRI can be made sensitive to the motion of molecules. Regular MRI acquisition utilizes the behavior of protons in water to generate contrast between clinically relevant features of a particular subject. The versatile nature of MRI is due to this capability of producing contrast related to the structure of tissues at the microscopic level.
The magnetic resonance frequency measured with an SWI scan was shown to be sensitive to MS lesion formation. The frequency increases months before a new lesion appears on a contrast enhanced scan. At the time of contrast enhancement the frequency increases rapidly and remains elevated for at least six months. [5] [6]
MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. [1]
I acknowledge that getting this scan is a major expense, and a privilege, as their scan prices start at $1,000. I should also note that not all experts think a full-body MRI scan is totally necessary.