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  2. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Several cell function specific transcription factors (there are about 1,600 transcription factors in a human cell [14]) generally bind to specific motifs on an enhancer [15] and a small combination of these enhancer-bound transcription factors, when brought close to a promoter by a DNA loop, govern level of transcription of the target gene.

  3. Translation (biology) - Wikipedia

    en.wikipedia.org/wiki/Translation_(biology)

    First, convert each template DNA base to its RNA complement (note that the complement of A is now U), as shown below. Note that the template strand of the DNA is the one the RNA is polymerized against; the other DNA strand would be the same as the RNA, but with thymine instead of uracil. DNA -> RNA A -> U T -> A C -> G G -> C A=T-> A=U

  4. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is ...

  5. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    Eukaryotic Transcription. Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1] Gene transcription occurs in both eukaryotic and prokaryotic cells. Unlike prokaryotic RNA polymerase that initiates the transcription of all ...

  6. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    These chemical changes alter the strength of the interaction between the DNA and the histones, making the DNA more or less accessible to transcription factors and changing the rate of transcription. [120] Other non-specific DNA-binding proteins in chromatin include the high-mobility group proteins, which bind to bent or distorted DNA. [121]

  7. Silencer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Silencer_(genetics)

    DNA contains genes and provides the template to produce messenger RNA (mRNA). That mRNA is then translated into proteins. When a repressor protein binds to the silencer region of DNA, RNA polymerase is prevented from transcribing the DNA sequence into RNA. With transcription blocked, the translation of RNA into proteins is impossible.

  8. Primary transcript - Wikipedia

    en.wikipedia.org/wiki/Primary_transcript

    The steps contributing to the production of primary transcripts involve a series of molecular interactions that initiate transcription of DNA within a cell's nucleus. Based on the needs of a given cell, certain DNA sequences are transcribed to produce a variety of RNA products to be translated into functional proteins for cellular use.

  9. Transcription-translation coupling - Wikipedia

    en.wikipedia.org/wiki/Transcription-translation...

    Translation promotes transcription elongation and regulates transcription termination. Functional coupling between transcription and translation is caused by direct physical interactions between the ribosome and RNA polymerase ("expressome complex"), ribosome-dependent changes to nascent mRNA secondary structure which affect RNA polymerase activity (e.g. "attenuation"), and ribosome-dependent ...

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