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Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.
Interleukin 6 (IL6), also referred to as B-cell stimulatory factor-2 (BSF-2) and interferon beta-2, is a cytokine involved in a wide variety of biological functions. [20] It plays an essential role in the final differentiation of B cells into immunoglobulin-secreting cells, as well as inducing myeloma/plasmacytoma growth, nerve cell ...
The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [6] IL6R subunit is also shared by many other cytokines.
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IL-6 had previously been classified as a proinflammatory cytokine. Therefore, it was first thought that the exercise-induced IL-6 response was related to muscle damage. [ 22 ] However, it has become evident that eccentric exercises are not associated with a larger increase in plasma IL-6 than exercise involving concentric “nondamaging ...
Hyper-IL-6 is a designer cytokine, which was generated by the German biochemist Stefan Rose-John. [1] Hyper-IL-6 is a fusion protein of the four-helical cytokine Interleukin-6 and the soluble Interleukin-6 receptor which are covalently linked by a flexible peptide linker. [1] Interleukin-6 on target cells binds to a membrane bound Interleukin-6 ...
Music video "Right Here, Right Now" on YouTube " Right Here, Right Now " is a song by British big beat musician Fatboy Slim , released on 19 April 1999 as the fourth single from his second studio album, You've Come a Long Way, Baby (1998).
The song's music video broke the records for the biggest music video premiere on YouTube, with 1.66 million concurrent viewers, and the most-watched music video within 24 hours, with 86.3 million views in its first day. [50] It became the fastest video to reach 100 million views, in just 32 hours, [51] and 200 million views, in seven days. [52]