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Amyl nitrites were part of some kits used to treat cyanide poisoning, containing amyl nitrite, sodium nitrite, and sodium thiosulfate. The nitrites were administered to produce methemoglobin and induce vasodilation. [40] [41] Amyl nitrites were discontinued in 2012 in standard cyanide kits. [42] Cyanide kits now use hydroxocobalamin. [43]
The term "amyl nitrite" encompasses several isomers.In older literature, the common non-systematic name amyl was often used for the pentyl group, where the amyl group is a linear or normal (n) alkyl group, and the resulting amyl nitrite would have the structural formula CH 3 (CH 2) 3 CH 2 ONO, also referred to as n-amyl nitrite.
Amyl nitrate is the chemical compound with the formula CH 3 (CH 2) 4 ONO 2. This molecule consists of the 5-carbon amyl group attached to a nitrate functional group . [ 1 ] It is the ester of amyl alcohol and nitric acid .
Alkyl nitrites were initially, and largely still are, used as medications and chemical reagents, a practice which began in the late 19th century. In their use as medicine, they are often inhaled for relief of angina and other heart-related symptoms of disease. However, when referred to as "poppers", alkyl nitrites represent recreational drugs.
Besides nitrates used to treat cardiovascular conditions, ED medications can interact with certain recreational drugs that contain nitrates, like amyl nitrate “poppers.” Interaction With ...
Nitrites such as alkyl nitrite originally came as small glass capsules that were popped open, which led to the nickname "poppers." The drug became popular in the US first on the disco /club scene of the 1970s, where dancers used the drug for the "rush" it provides, and because it was perceived to enhance the experience of dancing to loud, bass ...
Cohen also addressed the fact that “Rush” was inspired by poppers (the slang term for amyl nitrite, an inhalant that induces a euphoric feeling). Jonathan Groff Says He Came Out to His Brother.
Because of the risks of this medication, people taking alpha-blockers, over-the-counter nitrate supplements (like amyl nitrate, isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin) or ...