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The hepatic metabolism of excess alcohol leads to an increase in the level of endogenous toxins, [36] such as methanol, which is often present in homemade alcohol [37] This causes swelling of the eye and optic nerve and damage to the retina, especially in people who have underlying liver disease or who are already at risk for retinopathy due to ...
Apart from antimalarial effects, these drugs are also used in the treatment of other diseases such as dermatological, immunological, rheumatological, and severe infectious diseases. [25] Various ototoxic effects are manifested by using antimalarial drugs, with dizziness being one of the most common one.
Diabetes is the most common cause of retinopathy in the U.S. as of 2008. [4] Diabetic retinopathy is the leading cause of blindness in working-aged people. [5] It accounts for about 5% of blindness worldwide and is designated a priority eye disease by the World Health Organization. [6]
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
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Macular edema [11] and surgical re-attachment for macula-off rhegmatogenous retinal detachment [4] can also cause an increased separation of macular photoreceptor cells resulting in dysmetropsia. Retinoschisis is another eye disease that has been shown to cause aniseikonia.
Oculogyric crisis (OGC) is a rare sudden, paroxysmal, dystonic reaction that may manifest in response to specific drugs, particularly neuroleptics, or medical conditions, such as movement disorders. This neurological phenomenon is characterized by a sustained dystonic, conjugate , involuntary upward deviation of both eyes lasting seconds to hours.
Age-Related Macular Degeneration is a degenerative maculopathy associated with progressive sight loss. It is characterised by changes in pigmentation in the Retinal Pigment Epithelium, the appearance of drusen on the retina of the eye and choroidal neovascularization. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or ...