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Pepto-Bismol is an over-the-counter drug currently produced by the Procter & Gamble company in the United States, Canada and the United Kingdom. Pepto-Bismol is made in chewable tablets [ 24 ] and swallowable caplets, [ 25 ] but it is best known for its original formula, which is a thick liquid.
The company’s mixture called Cholera Infantum, later renamed Pepto-Bismol, appeared for the first time in 1901. Its principal use was for infants with severe diarrhea. In 1907, Acetylsalicylic acid tablets were added to the company’s product line.
The active ingredient in Kaopectate has changed since its original creation. Originally, kaolinite was used as the adsorbent and pectin as the emollient. Attapulgite (a type of absorbent clay) replaced the kaolinite in the 1980s, but was banned by the U.S. Food and Drug Administration in a ruling made in April 2003.
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Canada, UK Withdrawn from US in 2005 due to hepatotoxicity. [41] [3] Pentobarbital: 1980 Norway Risk of fatal overdose. [3] Pentylenetetrazol: 1982 US Withdrawn for inability to produce effective convulsive therapy, and for causing seizures. Pergolide (Permax) 2007 US Risk for heart valve damage. [2] Perhexiline: 1985 UK, Spain Neurologic and ...
A British aircraft carrier that had been set to lead the largest NATO exercises since the Cold War will not set sail Sunday after a problem with its propeller was discovered during final checks ...
Bismuth subsalicylate is used to treat diarrhea; [9] it is the active ingredient in such "pink bismuth" preparations as Pepto-Bismol, as well as the 2004 reformulation of Kaopectate. It is also used to treat some other gastro-intestinal diseases like shigellosis [72] and cadmium poisoning. [9]
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