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Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, response surface methodology (RSM) explores the relationships between several explanatory variables and one or more response variables. RSM is an empirical model which employs the use of mathematical and statistical ...
Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, a full factorial experiment is an experiment whose design consists of two or more factors, each with discrete possible values or "levels", and whose experimental units take on all possible combinations of these levels across all such factors.
The same is true for intervening variables (a variable in between the supposed cause (X) and the effect (Y)), and anteceding variables (a variable prior to the supposed cause (X) that is the true cause). When a third variable is involved and has not been controlled for, the relation is said to be a zero order relationship. In most practical ...
In QSAR modeling, the predictors consist of physico-chemical properties or theoretical molecular descriptors [1] [2] of chemicals; the QSAR response-variable could be a biological activity of the chemicals. QSAR models first summarize a supposed relationship between chemical structures and biological activity in a data-set of chemicals
The model for the response is , = + + with Y i,j being any observation for which X 1 = i (i and j denote the level of the factor and the replication within the level of the factor, respectively) μ (or mu) is the general location parameter; T i is the effect of having treatment level i
In some disciplines (e.g., psychology or political science), a 'true experiment' is a method of social research in which there are two kinds of variables. The independent variable is manipulated by the experimenter, and the dependent variable is measured.
The response factor can be expressed on a molar, volume or mass [1] basis. Where the true amount of sample and standard are equal: = where A is the signal (e.g. peak area) and the subscript i indicates the sample and the subscript st indicates the standard. [2]
It is also possible in some cases to fix the problem by applying a transformation to the response variable (e.g., fitting the logarithm of the response variable using a linear regression model, which implies that the response variable itself has a log-normal distribution rather than a normal distribution).