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5515 19052 Ensembl ENSG00000113575 ENSMUSG00000020349 UniProt P67775 P63330 RefSeq (mRNA) NM_002715 NM_001355019 NM_019411 RefSeq (protein) NP_002706 NP_001341948 NP_062284 Location (UCSC) Chr 5: 134.19 – 134.23 Mb Chr 11: 51.99 – 52.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in ...
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral ...
Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [ 2 ] [ 3 ] The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. [ 4 ]
1369 93721 Ensembl ENSG00000120054 ENSMUSG00000025196 UniProt P15169 Q9JJN5 RefSeq (mRNA) NM_001308 NM_030703 RefSeq (protein) NP_001299 NP_109628 Location (UCSC) Chr 10: 100.04 – 100.08 Mb Chr 19: 43.94 – 43.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene. Carboxypeptidase N is a plasma ...
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription.
Catalytic triads have also been inserted into otherwise non-catalytic proteins, or protein mimics. [ 48 ] Subtilisin (a serine protease) has had its oxygen nucleophile replaced with each of sulfur, [ 49 ] [ 50 ] selenium , [ 51 ] or tellurium . [ 52 ]
The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. [1] As a system of enzyme nomenclature, every EC number is associated with a recommended name for the corresponding enzyme-catalyzed reaction.
Aspartate carbamoyltransferase (also known as aspartate transcarbamoylase or ATCase) catalyzes the first step in the pyrimidine biosynthetic pathway (EC 2.1.3.2). [1]In E. coli, the enzyme is a multi-subunit protein complex composed of 12 subunits (300 kDa in total). [2]