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Survival analysis is a branch of statistics for analyzing the expected duration of time until one event occurs, such as death in biological organisms and failure in mechanical systems. This topic is called reliability theory , reliability analysis or reliability engineering in engineering , duration analysis or duration modelling in economics ...
In full generality, the accelerated failure time model can be specified as [2] (|) = ()where denotes the joint effect of covariates, typically = ([+ +]). (Specifying the regression coefficients with a negative sign implies that high values of the covariates increase the survival time, but this is merely a sign convention; without a negative sign, they increase the hazard.)
a 8.3x higher risk of death does not mean that 8.3x more patients will die in hospital A: survival analysis examines how quickly events occur, not simply whether they occur. More specifically, "risk of death" is a measure of a rate. A rate has units, like meters per second.
In survival analysis, the hazard ratio (HR) is the ratio of the hazard rates corresponding to the conditions characterised by two distinct levels of a treatment variable of interest. For example, in a clinical study of a drug, the treated population may die at twice the rate of the control population.
The log-logistic distribution provides one parametric model for survival analysis. Unlike the more commonly used Weibull distribution , it can have a non- monotonic hazard function : when β > 1 , {\displaystyle \beta >1,} the hazard function is unimodal (when β {\displaystyle \beta } ≤ 1, the hazard decreases monotonically).
This distribution can be used to analyze time-to-event data in biomedical and public health areas and normally called survival analysis. In engineering, the time-to-event analysis is referred to as reliability theory and in business and economics it is called duration analysis. Other fields may use different names for the same analysis.
In mathematical statistics, the survival function is one specific form of survivorship curve and plays a basic part in survival analysis. There are various reasons that a species exhibits their particular survivorship curve, but one contributor can be environmental factors that decrease survival.
The relative survival form of analysis is more complex than "competing risks" but is considered the gold-standard for performing a cause-specific survival analysis. It is based on two rates: the overall hazard rate observed in a diseased population and the background or expected hazard rate in the general or background population.