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Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. [1] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to ...
Skeletal structural formula of Vitamin B 12.Many organic molecules are too complicated to be specified by a molecular formula.. The structural formula of a chemical compound is a graphic representation of the molecular structure (determined by structural chemistry methods), showing how the atoms are connected to one another. [1]
The structure of the sulfonamide group. In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure R−S(=O) 2 −NR 2. It consists of a sulfonyl group (O=S=O) connected to an amine group (−NH 2). Relatively speaking this group is unreactive.
In this example, the reactants are aniline, triethylamine (Et 3 N, Et = ethyl group), and iodine. Sulfur dioxide is believed to be activated through a series of intermediates: Et 3 N− + −I −, Et 3 N−I + −I − 3 and Et 3 N + −SO − 2. The sulfamide functional group is an increasingly common structural feature used in medicinal ...
Tosylamide/formaldehyde resin (TSFR) is a polymeric resin used as a plasticizer and secondary film-forming agent in nail polishes.While it was still in use as of 2023, its use has been diminishing in favor of hypoallergenic alternatives, due to the prevalence of reactions causing allergic contact dermatitis of the eyelids, face, and neck.
Sulfamethoxazole, a sulfanilamide, is a structural analog of para-aminobenzoic acid (PABA). They compete with PABA to bind to dihydropteroate synthetase and inhibit conversion of PABA and dihydropteroate diphosphate to dihydrofolic acid, or dihydrofolate.
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