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The goal is to increase the urine volume because the concentration of cystine in the urine is reduced which prevents cystine from precipitating from the urine and forming stones. People with cystine stones should consume 5 to 7 liters a day. The rationale behind alkalizing the urine is that cystine tends to stay in solution and causes no harm ...
Cystine crystals are hexagonal in shape and are colorless. They are not found often in alkaline urine due to their high solubility. The colorless crystals can be difficult to distinguish from uric acid crystals which are also hexagonal. Under polarized examination, the crystals are birefringent with a polarization color interference. [9]
People with certain rare inborn errors of metabolism have a propensity to accumulate crystal-forming substances in their urine. For example, those with cystinuria, cystinosis, and Fanconi syndrome may form stones composed of cystine. Cystine stone formation can be treated with urine alkalinization and dietary protein restriction.
Cystine ((SCH 2 CHNH 2 COOH) 2) stones form in an acidic to neutral urine. They are usually smooth and round. They are caused by increased urine excretion of cystine (a relatively insoluble amino acid) in dogs with a defect in renal tubule reabsorption of cystine. Dietary reduction of protein and alkalinization of the urine may help prevent ...
Crystalluria refers to crystals found in the urine when performing a urine test. Crystalluria is considered often as a benign condition and as one of the side effects of sulfonamides and penicillins. The main reason for the identification of urinary crystals is to detect the presence of the relatively few abnormal types that may represent a ...
Leucine and tyrosine crystals may be observed in liver disease, [24] and cystine crystals indicate cystinuria (although they look identical to hexagonal variants of uric acid crystals, and can only be distinguished with further testing). [127] Cholesterol crystals may rarely be seen in nephrotic syndrome and chyluria. [128]
The most common type of cast, hyaline casts are solidified Tamm–Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and as such, they may be seen in normal individuals in dehydration or vigorous exercise.
These stones are most commonly made up of substances such as calcium, cystine, oxalate, and uric acid, as these are the substances that normally would dissolve within the urine. When they do not dissolve correctly and further build up, they will commonly lodge themselves in the urinary tract and in this case, are usually small enough to pass ...