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  2. History of neuraxial anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_neuraxial...

    "Anesthesia of nerve roots with cocaine". Cleveland Medical Journal. 2: 355. Cushing, HW (1902). "I. On the Avoidance of Shock in Major Amputations by Cocainization of Large Nerve-Trunks Preliminary to their Division. With Observations on Blood-Pressure Changes in Surgical Cases". Annals of Surgery. 36 (3): 321– 45. doi:10.1097/00000658 ...

  3. Karl Koller (ophthalmologist) - Wikipedia

    en.wikipedia.org/wiki/Karl_Koller_(ophthalmologist)

    Koller introduced cocaine as a local anaesthetic for eye surgery. Prior to this discovery, he had tested solutions such as chloral hydrate and morphine as anaesthetics in the eyes of laboratory animals without success. Freud was fully aware of the pain-killing properties of cocaine, but Koller recognized its tissue-numbing capabilities, and in ...

  4. Anesthesia - Wikipedia

    en.wikipedia.org/wiki/Anesthesia

    Cocaine was later isolated and became the first effective local anesthetic. It was first used in eye surgery in 1884 by Karl Koller, at the suggestion of Sigmund Freud. [39] German surgeon August Bier (1861–1949) was the first to use cocaine for intrathecal anesthesia in 1898. [40]

  5. Spinal anaesthesia - Wikipedia

    en.wikipedia.org/wiki/Spinal_anaesthesia

    The first planned spinal anaesthesia for surgery on a human was administered by August Bier (1861–1949) on 16 August 1898, in Kiel, when he injected 3 ml of 0.5% cocaine solution into a 34-year-old labourer. [14] After using it on six patients, he and his assistant each injected cocaine into the other's spine. They recommended it for ...

  6. Cocaine-induced midline destructive lesions - Wikipedia

    en.wikipedia.org/wiki/Cocaine-Induced_Midline...

    The only reliable treatment of CIMDL is cessation of cocaine abuse, which is considered a necessary prerequisite for surgical reconstruction. If abstention can be achieved, reconstructive surgery, prosthetics and medical therapy can achieve satisfactory results.

  7. Kaley Cuoco reveals past addiction that led to major surgery

    www.aol.com/entertainment/2015-01-14-kaley-cuoco...

    Kaley Cuoco went on "The Ellen Degeneres Show" and revealed a past addiction that ultimately led to some serious surgery. Cuoco went under the knife over the holidays for her sinuses and told ...

  8. History of surgery - Wikipedia

    en.wikipedia.org/wiki/History_of_surgery

    Surgery is the branch of medicine that deals with the physical manipulation of a ... Austrian ophthalmologist Karl Koller first used cocaine as a local anesthetic for ...

  9. Over $239 million worth of cocaine, including from a narco ...

    www.aol.com/news/over-239-million-worth-cocaine...

    The cocaine has an estimated street value of more than $239 million. It was recovered off the coasts of Mexico, Central America, and South America by two U.S. Coast Guard ships in November, the ...