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Bis(chloroethyl) ether can be used in the synthesis of the cough suppressant fedrilate. It is combined with benzyl cyanide and two molar equivalents of sodamide in a ring-forming reaction. When treated with strong base, it gives divinyl ether, an anesthetic: [5] O(CH 2 CH 2 Cl) 2 + 2 KOH → O(CH=CH 2) 2 + 2 KCl + 2 H 2 O
Bis(2-chloroethyl)ethylamine is the organic compound with the formula C 2 H 5 N(CH 2 CH 2 Cl) 2.Often abbreviated HN1, it is a powerful vesicant and a nitrogen mustard gas. HN1 was developed in the 1920s and 1930s to remove warts and later as a military agent.
Bis(chloromethyl) ether is an organic compound with the chemical formula (ClCH 2) 2 O. It is a colourless liquid with an unpleasant suffocating odour and it is one of the chloroalkyl ethers . Bis(chloromethyl) ether was once produced on a large scale, but was found to be highly carcinogenic and thus such production has ceased.
Chemical structure of chloromethyl methyl ether (MOM-Cl) Chloroalkyl ethers are a class of organic compounds with the general structure R-O-(CH 2) n-Cl, characterized as an ether connected to a chloromethyl group via an alkane chain. Chloromethyl methyl ether (CMME) is an ether with the formula C H 3 OCH 2 Cl.
The effect of vesicant (blister) agents in the form of mustard gas (sulfur mustard, Bis(2-chloroethyl) sulfide) on bone marrow and white blood cells had been known since the First World War. [16] In 1935 several lines of chemical and biological research yielded results that would be explored after the start of the Second World War.
Bis(2-chloroethyl)sulfide is the organosulfur compound with the formula (ClCH 2 CH 2) 2 S. It is a prominent member of a family of cytotoxic and blister agents known as mustard agents. Sometimes referred to as mustard gas , the term is technically incorrect: bis(2-chloroethyl)sulfide is a liquid at room temperature.
Carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma, multiple myeloma, and lymphoma (Hodgkin's and non-Hodgkin).
1,1-Bis(chloromethyl)ethylene is the organic compound with the formula CH 2 =C(CH 2 Cl) 2. It is a colorless liquid. It is a colorless liquid. Featuring two allylic chloride substituents, it is di alkylating agent .