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[3] [8] The drug is available both by prescription and at lower doses over the counter. [2] [16] [4] [17] Besides for UTI prevention, methenamine is also available in a topical form to treat hyperhidrosis. [5] [6] [18] Side effects of methenamine are generally minor and include upset stomach, nausea, and headache, among others.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
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The term over-the-counter (OTC) refers to a medication that can be purchased without a medical prescription. [3] In contrast, prescription drugs require a prescription from a doctor or other health care professional and should only be used by the prescribed individual. [4]
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