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  2. Mandibular advancement splint - Wikipedia

    en.wikipedia.org/wiki/Mandibular_advancement_splint

    The high price for prescription devices has led to a proliferation of lower cost non-prescription devices that are unproven and some sleep specialists suggest may be dangerous. [ 16 ] Adherence to oral appliance is strongly associated with patient reservations regarding the effects of the device on teeth, possible lack of efficacy, and discomfort.

  3. Snoring - Wikipedia

    en.wikipedia.org/wiki/Snoring

    Snoring is the vibration of respiratory structures and the resulting sound due to obstructed air movement during breathing while sleeping. The sound may be soft or loud and unpleasant. Snoring during sleep may be a sign, or first alarm, of obstructive sleep apnea (OSA). Research suggests that snoring is one of the factors of sleep deprivation.

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  5. Obstructive sleep apnea - Wikipedia

    en.wikipedia.org/wiki/Obstructive_sleep_apnea

    Snoring and witnessed apnea are more frequent among men but insomnia for example is more frequent among women. [66] The OSA frequency increase with age for the women. [66] The mortality is higher for women. [66] Some studies report that it is more frequent among the Hispanic and African American population than among the white population. [66]

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  7. Sodium oxybate - Wikipedia

    en.wikipedia.org/wiki/Sodium_oxybate

    As of 2017 the cost of sodium oxybate in the UK was £540.00 to £1,080.00 for a thirty-day supply, [66] which at typical doses is £6,500 to £13,100 per year. [67] Jazz Pharmaceuticals raised the price of Xyrem 841% earning a total of $569 million in 2013 and representing more than 50% of Jazz Pharmaceutical's revenues. [14]