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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum.The word is from Ancient Greek κρυπτός (kryptos) 'hidden' and ὄρχις (orchis) 'testicle'.
The ectopic testis can be in the perineal region, the opposite side of the scrotum, the suprapubic region, the femoral region, or the superficial inguinal pouch. [1]The ectopic testis is initially normal, but if it is ignored after childhood, it may become small and soft, with spermatogenesis arresting and interstitial cell proliferation occurring.
The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum. Cryptorchidism (undescended testes) are observed in INSL3-null male mice.
The rete testis (/ ˈ r iː t i ˈ t ɛ s t ɪ s / REE-tee TES-tis; pl.: retia testes) is an anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the efferent ducts. It is the homologue of the rete ovarii in females. [1]
In this case the testis is within the abdominal cavity, somewhere along the normal route of descent – most commonly, within the inguinal canal. Such a testis has an increased risk of malignancy . One testicle may disappear during development (the so-called vanishing testis ) due to some intrauterine insult.
The undescended testis is at increased risk of testicular torsion. [17] The mechanism for torsion in the undescended testicle is not fully understood, though it may be due to abnormal contractions of the cremaster muscle, which covers the testicle and spermatic cord and is responsible for raising and lowering the testicle to regulate scrotal ...
The tunica albuginea is a dense, [1] [2] blue-white [3] layer of fibrous tissue surrounding the testis. [1] [4] It is the middle of three envelopes forming the capsule of the testis; it is deep to the visceral layer of tunica vaginalis, and superficial to the tunica vasculosa testis (vascular layer of testis).
The descent of the testicles consists of the opening of a connection from the testis to its final location at the anterior abdominal wall, followed by the development of the gubernaculum, which subsequently pulls and translocates the testicle down into the developing scrotum. Ultimately, the passageway closes behind the testis.