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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Due to a successful marketing campaign, thalidomide was widely used by pregnant women during the first trimester of pregnancy. However, thalidomide is a teratogenic substance, and a proportion of children born during the 1960s had thalidomide embryopathy (TE). [90] Of these babies born with TE, "about 40% of them died before their first ...
Frances Kathleen Oldham Kelsey CM (née Oldham; July 24, 1914 – August 7, 2015) was a Canadian-American [1] pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding the drug's safety. [2]
Thalidomide victim, right; Sen. Kefauver and President-elect Kennedy, 1960 Associated Press and Joun Rous/Associated Press. A key provision of the new law made it a crime for drug companies to promote drugs to doctors for patients with illnesses for which the drug, according to its FDA-approved label, was not intended and approved for use.
The directive was a reaction [citation needed] to the Thalidomide tragedy in the early 1960s, when thousands of babies were born with deformities as a result of their mothers taking the drug during pregnancy.
The tradition of U.S. women taking their husband’s last names reaches back to English common law, according to Baker. The practice is rooted in coverture, a legal doctrine under which a woman ...
Chessen took 36 of the pills in the early stages of her fifth pregnancy, unaware that they contained thalidomide, [1] which could cause deformity in the fetus. [2] Her physician recommended that she obtain a therapeutic abortion , [ 3 ] the only type permitted in Arizona at the time.
19 th Amendment. Women in the U.S. won the right to vote for the first time in 1920 when Congress ratified the 19th Amendment.The fight for women’s suffrage stretched back to at least 1848, when ...