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The lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride per kg body weight). [53] [54] [55] A case of a fatal poisoning of an adult with 4 grams of sodium fluoride is documented, [56] and a dose of 120 g sodium fluoride has been survived. [57]
[10] [11] [12] Of 2,945 children examined in 1909 by Dr. McKay, 87.5% had some degree of stain or mottling. All the affected children were from the Pikes Peak region. Despite the negative impact on the physical appearance of their teeth, the children with stained, mottled and pitted teeth also had fewer cavities than other children.
Fluoride's adverse effects depend on total fluoride dosage from all sources. At the commonly recommended dosage, the only clear adverse effect is dental fluorosis , which can alter the appearance of children's teeth during tooth development ; this is mostly mild and is unlikely to represent any real effect on aesthetic appearance or on public ...
After fluoride was added in many places to the U.S. water supply, tooth decay declined in both children and adults, and complete tooth loss in older adults became more rare, according to federal ...
Elevated prenatal exposure to fluoride was associated with increased risk of neurobehavioral problems in 3-year-olds, according to a study of children in Los Angeles.
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A 2019 study, published in a well-respected journal, JAMA Pediatrics, found that IQ levels were slightly lower in 3- and 4-year-old children whose mothers had higher measures of fluoride in their ...
In a landmark case, Fluoride Action Network and other health advocacy groups successfully argued that fluoride levels currently promoted as “optimal” by the EPA and other government agencies pose a significant threat to public health, particularly to the cognitive development of children. The United States District Court for the Northern ...