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Illustration depicting ankylosing spondylitis. The signs and symptoms of ankylosing spondylitis often appear gradually, with peak onset between 20 and 30 years of age. [11] Initial symptoms are usually a chronic dull pain in the lower back or gluteal region combined with stiffness of the lower back. [12]
Among the genetic factors that may influence ankylosing spondylitis, the HLA-B27 gene accounts for about thirty percent of the overall genetic risk, per the National Library of Medicine. The ...
Ankylosing spondylitis (AS) is a type of arthritis in which there is long-term inflammation of the joints of the spine. Typically the joints where the spine joins the pelvis are also affected. Occasionally other joints such as the shoulders or hips are involved. [1] John Addey (1920–1982), [2] English astrologer
Ankylosing spondylitis is a genetic disease with identifiable marks, tends to start showing signs in adolescence or young adulthood, is more likely to affect the lumbar spine, and affects organs. DISH has no indication of a genetic link, is primarily thoracic and does not affect organs other than the lungs, and only indirectly due to the fusion ...
In 1994, a research team consisting of rheumatologists, physiotherapists, and others with a special interest in Ankylosing Spondylitis, developed the index in Bath, England (hence the reason for "Bath" in the name), describing a self-administered 6-question measurement tool that later become the gold standard for measuring and evaluating AS disease activity.
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
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