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The exact mechanism of the condition is unknown. Some studies have suggested the itching occurs in response to increased fibrinolytic activity in the skin, [5] [6] inappropriate activation of the sympathetic nervous system, [7] increased activity of acetylcholinesterase, [8] [9] or an increase in mast cell degranulation that releases histamine and other chemicals into the body.
High concentration topical capsaicin (8%, Qutenza) have been shown to be highly effective in treating neuropathic itch in some patients [12] [13] (including notalgia paresthetica) as well as in a recent proof-of-concept study. [14] Most recently intradermal injections of botulinum toxin type A (Botox) have been tried with some success. Even ...
Scabies (/ ˈ s k eɪ b iː z, ˈ s k eɪ b i iː z /; [10] also sometimes known as the seven-year itch) [1] is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite Sarcoptes scabiei, [1] [3] variety hominis. The word is from Latin: scabere, lit. 'to scratch'. [11] The most common symptoms are severe itchiness and a pimple-like ...
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Ringworm. What it looks like: Ringworm is a common skin infection caused by a fungus. It gets its name from its circular rash, which is often red, swollen, and cracked. Other symptoms to note ...
Clusters of small bites on the ankles could signal chiggers while larger welts on exposed arms and legs ... itchy bumps. A severe allergic reaction may come with a hive-like rash, swelling and ...