Ads
related to: which statin can be used with gemfibrozil medication for arthritis- See Treatment Results
Help Relieve Your RA Symptoms
With A Once-Daily Oral Pill.
- Discover An RA Treatment
Still Experiencing RA Symptoms?
A Treatment Plan Change May Help.
- Find A Rheumatologist
Find A Rheumatologist Near You.
Set Goals For RA Treatment.
- Injection-Free Treatment
RA TNF Blocker Didn't Work For You?
See How A JAK Inhibitor May Help.
- See Treatment Results
Search results
Results From The WOW.Com Content Network
Gemfibrozil, sold under the brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. [3] It is generally less preferred than statins. [3] [4] Use is recommended together with dietary changes and exercise. [3] It is unclear if it changes the risk of heart disease. [3] It is taken by mouth. [3]
However, the risk was over 10-fold greater if cerivastatin was used, or if the standard statins (atorvastatin, fluvastatin, lovastatin, pravastatin, or simvastatin) were combined with a fibrate (fenofibrate or gemfibrozil) treatment. Cerivastatin was withdrawn by its manufacturer in 2001.
Among atypical adverse effects, myositis can occur in patients under gemfibrozil therapy, especially in those with renal insufficiency or under co-treatment with statins. In contrast, the risk of myopathy is much lower if fenofibrate is used in replacement of gemfibrozil owing to its different pharmacokinetic pathway.
In studies using standard doses, statins have been found to lower LDL-C by 18% to 55%, depending on the specific statin being used. A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after ...
[3] [16] [17] This risk also appears to increase among patients who received gemfibrozil [3] [18] or lovastatin [16] concomitantly, and there is a known interaction between these drugs and cerivastatin. There are 31 cerivastatin-related deaths reported in the US and a further 21 deaths worldwide.
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug.In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [1]
Ad
related to: which statin can be used with gemfibrozil medication for arthritis