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Diabetic nephropathy, damage to the kidney due to increased glomerular pressure and hyperfiltration can lead to end-stage chronic kidney disease that may require renal dialysis. [27] In most parts of the world, diabetes mellitus is the leading cause of end-stage kidney disease (ESKD).
Diabetic nephropathy is the most common cause of end-stage renal disease and is a serious complication that affects approximately one quarter of adults with diabetes in the United States. [ 13 ] [ 14 ] Affected individuals with end-stage kidney disease often require hemodialysis and eventually kidney transplantation to replace the failed kidney ...
The long-term complications associated with type 2 diabetes, like damage to your organs, can begin during prediabetes. So, despite the “pre,” it’s still a serious health condition.
Sarcoidosis: This disease does not usually affect the kidney but, on occasions, the accumulation of inflammatory granulomas (collection of immune cells) in the glomeruli can lead to nephrotic syndrome. Syphilis: kidney damage can occur during the secondary stage of this disease (between 2 and 8 weeks from onset).
If left untreated, the disease can lead to various health complications, including disorders of the cardiovascular system, eye, kidney, and nerves. [3] Diabetes accounts for approximately 4.2 million deaths every year, [9] with an estimated 1.5 million caused by either untreated or poorly treated diabetes. [10]
If left untreated, diabetes can cause many complications. [5] Complications of relatively rapid onset include diabetic ketoacidosis and nonketotic hyperosmolar coma . [ 11 ] Long-term complications include heart disease , stroke, kidney failure , foot ulcers , and damage to the eyes . [ 5 ]
Lower socio‐economic status and higher area‐level deprivation are associated with an increased risk of diabetic ketoacidosis in people with diabetes mellitus type 1. [ 43 ] Previously considered universally fatal, the risk of death with adequate and timely treatment is between <1% and 5%.
Chronic hyperglycemia at above normal levels can produce a very wide variety of serious complications over a period of years, including kidney damage, neurological damage, cardiovascular damage, damage to the retina or damage to feet and legs. Diabetic neuropathy may be a result of long-term hyperglycemia. Impairment of growth and ...