Ads
related to: what causes narcolepsy and cataplexy- Cataplexy in Narcolepsy
Gain more insights into the signs
and symptoms of cataplexy.
- Clinical Assessment
See clinical interview strategies
for identifying ongoing symptoms.
- Diagnosis Resources
View diagnostic criteria for
narcolepsy and find ICD-10 codes.
- Regulating Wakefulness
Discover the role of wake-promoting
neurons in sleep-wake cycle.
- EDS and Narcolepsy
Excessive daytime sleepiness
is more than just falling asleep.
- Narcolepsy Neurobiology
Sleep-wake state stability, role of
the hypothalamus and histamine.
- Cataplexy in Narcolepsy
Search results
Results From The WOW.Com Content Network
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
Cataplexy is the first symptom to appear in about 10% of cases of narcolepsy, [2] caused by an autoimmune destruction of hypothalamic neurons that produce the neuropeptide hypocretin (also called orexin), which regulates arousal and has a role in stabilization of the transition between wake and sleep states. [3]
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
Experts say cataplexy, which is a loss of muscle tone, often accompanies narcolepsy. ... About 1 in 2000 people suffer from narcolepsy in the United States. The cause of Sarah's type narcolepsy is ...
Usually, people with this disorder have ataxia, mild–moderate sensorineural hearing loss, narcolepsy, and cataplexy. These symptoms start happening when an affected person is about 30 years old. [6] [7] A bit later in life, people with ADCADN start showing a decline in executive function known as dementia.
Pediatric narcolepsy cases are cases when patients are diagnosed or experience symptoms onset for narcolepsy before the age of 18. Of patients who obtain a formal diagnosis for narcolepsy, more than 50% report first experiencing symptoms of narcolepsy more than 10 years before their formal diagnosis, with an average age of symptom onset being at age 15 and symptom onset most likely to occur ...
Ads
related to: what causes narcolepsy and cataplexy