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The sodium–potassium pump (sodium–potassium adenosine triphosphatase, also known as Na + /K +-ATPase, Na + /K + pump, or sodium–potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells. It performs several functions in cell physiology. The Na + /K +-ATPase enzyme is active (i.e. it ...
Ouabain is a cardiac glycoside that acts by non-selectively inhibiting the Na + /K +-ATPase sodium–potassium ion pump. [2] Once ouabain binds to this enzyme, the enzyme ceases to function, leading to an increase of intracellular sodium.
Amino acids and sugars are taken up from sea water in the presence of extracellular sodium and is driven by the NA + /K +-ATPase pump. [ 1 ] In the roots of plants , the H+/K+ symporters are only one member of a group of several symporters/antiporters that specifically allow only one charged hydrogen ion (more commonly known as a proton) and ...
Nomenclature and some functions of voltage-gated sodium channel beta subunits Protein name Gene link Assembles with Expression profile Associated human channelopathies; Na v β1: SCN1B: Na v 1.1 to Na v 1.7: Central Neurons, Peripheral Neurons, skeletal muscle, heart, glia: epilepsy (GEFS+), Brugada syndrome [34] Na v β2: SCN2B: Na v 1.1, Na v ...
Diffusion vs. Transport. In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different biological functions, including cellular communication, maintaining homeostasis, energy production, etc. [1] There are different types of transporters including pumps, uniporters, antiporters, and symporters.
The SGLT functions to couple the transport of sodium in the exoplasmic space down its concentration gradient (again, established by the active transport of sodium out of the cell by the sodium-potassium pump) into the cytoplasmic space to the transport of glucose in the exoplasmic space against its concentration gradient into the cytoplasmic ...
The sodium–potassium pump, a critical enzyme for regulating sodium and potassium levels in cells. Sodium ions (Na +) are necessary in small amounts for some types of plants, [1] but sodium as a nutrient is more generally needed in larger amounts [1] by animals, due to their use of it for generation of nerve impulses and for maintenance of electrolyte balance and fluid balance.
At the resting voltage potential, a pump is pumping 2 K+ ions into the cell, and pumps 3 Na+ ions out of the cell. Since this is a nett electrical current, it makes the cell's membrane voltage slightly more negative. This causes a passive influx of 1 K+ ion, driven by the membrane voltage.