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A 2014 review said there was some evidence men with certain comorbidities may be at risk of adverse effects including sleep apnoea, metabolic syndrome and cardiovascular disease. [29] Exogenous testosterone may also cause suppression of spermatogenesis, leading to, in some cases, infertility. [30]
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
107221 Ensembl ENSG00000186188 ENSMUSG00000054200 UniProt Q5NUL3 Q7TMA4 RefSeq (mRNA) NM_001195755 NM_181745 NM_181748 RefSeq (protein) NP_001182684 NP_859529 NP_861413 Location (UCSC) Chr 10: 93.57 – 93.6 Mb Chr 19: 38.09 – 38.1 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein ...
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The AR plays a role in regulating female sexual, somatic, and behavioral functions. Experimental data using AR knockout female mice, provides evidence that the promotion of cardiac growth, kidney hypertrophy, cortical bone growth and regulation of trabecular bone structure is a result of DNA-binding-dependent actions of the AR in females.
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