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Infant botulism (also referred to as floppy baby syndrome) was first recognized in 1976, and is the most common form of botulism in the United States. Infants are susceptible to infant botulism in the first year of life, with more than 90% of cases occurring in infants younger than six months. [4]
Severe hypotonia in infancy is commonly known as floppy baby syndrome. Recognizing hypotonia, even in early infancy , is usually relatively straightforward, but diagnosing the underlying cause can be difficult and often unsuccessful.
If infant botulism is related to food, such as honey, problems generally begin within 18 to 36 hours after the toxin enters the baby's body. Signs and symptoms include: [65] [70] Constipation (often the first sign) Floppy movements due to muscle weakness and trouble controlling the head; Weak cry; Irritability; Drooling; Ptosis; Tiredness
The health department said the cases are being investigated.
Clostridium baratii is an anaerobic, motile, gram-positive bacterium.It is a rare cause of infant botulism, in which newborns or infants lose their muscle tone, and develop trouble feeding due to a difficulty in breathing, which can be fatal.
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One doctor said the patient, now 16 months old, looks like “any typically developing baby at this age.” With help from Duke doctors, a rare genetic disease is treated in the womb for the first ...
However, the toxin can also be introduced through an infected wound. In infants, the bacteria can sometimes grow in the intestines and produce botulinum toxin within the intestine and can cause a condition known as floppy baby syndrome. [87] In all cases, the toxin can then spread, blocking nerves and muscle function.