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A drug combination chart designed for harm reduction by TripSit [1] Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals.
The illegal drug trade, drug trafficking, or narcotrafficking is a global black market dedicated to the cultivation, manufacture, distribution and sale of prohibited drugs. Most jurisdictions prohibit trade, except under license , of many types of drugs through the use of drug prohibition laws .
Fenethylline is now illegal in most countries; it is produced primarily for illicit use, which takes place mainly in the Middle East, with some evidence that it is used by Islamist Terrorists. The illicit global market for the drug was estimated in 2023 to be worth approximately US$ 57 billion. [ 4 ]
It is, however, regulated by the Food and Drug Administration under the Food Drug and Cosmetics Act. Prosecution is possible under its "misbranding" clauses, prohibiting the sale or distribution of nitrous oxide for the purpose of human consumption (the recreational drug use market). Given the necessity of proving the intent of either buyer or ...
In the draft guidance, the FDA encouraged drug companies to launch clinical trials for cocaine, methamphetamine and prescription stimulant addictions. Promising drugs could qualify for expedited ...
Crack users tend to smoke the drug because that has a higher bioavailability than other routes typically used for drugs of abuse, such as insufflation. Crack has a melting point of around 90 °C (194 °F), [1] and the smoke does not remain potent for long. Therefore, crack pipes are generally very short, to minimize the time between evaporating ...
Bag and contents of a well-known early brand of synthetic cannabinoids named Spice that contains herbs covered with synthetic cannabinoids, now illegal throughout much of the world. Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants ...
Two Indian chemical companies have been indicted for allegedly importing ingredients for the highly addictive opioid fentanyl into the United States and Mexico, the U.S. Department of Justice said ...