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Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [ 2 ] [ 3 ] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia , and methanol poisoning .
These 2 chemotherapy protocols are very similar in principle. Both consist of 3 medicinal drugs: a) Leucovorin (= folinic acid = calcium folinate), b) 5-Fluorouracil (= 5-FU), and c) Oxaliplatin. Since these 3 medicinal drugs are "concomitant" to each other, such a constellation is called "concomitant drugs". [1]
Researchers discovered that consuming an additional 300 milligrams (mg) of calcium each day, the equivalent of around 1 glass of milk, was associated with a 17% lowered risk for colorectal cancer.
Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). [12] It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease [12] (a type of cutaneous squamous-cell carcinoma), and as eye drops for treatment of ocular surface squamous neoplasia. [13]
“There are many different foods that are good sources of calcium,” says Katherine Zeratsky, R.D.N., a clinical dietitian at Mayo Clinic. “Reading the label can help you make good decisions ...
With the price of eggs rising and shortages being reported at grocery stores around the U.S., hungry consumers may need to look outside the box, or shell, for alternatives. The average price of a ...
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