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Over time, insulin resistance and high blood sugar—two characteristics of diabetes—can damage blood vessels and impact nitric oxide production, which L-arginine supplements may help counter ...
Diabetic cardiomyopathy, damage to the heart muscle, leading to impaired relaxation and filling of the heart with blood (diastolic dysfunction) and eventually heart failure; this condition can occur independent of damage done to the blood vessels over time from high levels of blood glucose.
Arteries and veins of the penis. The penile artery (also known as the common penile artery) is the artery that serves blood to the penis. It is a terminal branch of the internal pudendal artery, along with the scrotal artery. It subdivides into three arteries, the bulbourethral artery, the dorsal artery of the penis and the cavernosal artery.
The corpora cavernosa are innervated by lesser and greater cavernous nerves and form most of the penis containing blood vessels that fill with blood to help make an erection. [8] The crura are the proximal parts of the corpora cavernosa. The corpus spongiosum is an erectile tissue surrounding the urethra.
Venous leak is an inability to maintain an erection in the presence of sufficient arterial blood flow through the cavernosal arteries of the penis. [6] The defect lies in the excessive drainage of veins in the cavernosal tissue of the penis, which undermines normal erectile function.
Nitric oxide (NO) contributes to vessel homeostasis by inhibiting vascular smooth muscle contraction and growth, platelet aggregation, and leukocyte adhesion to the endothelium. Humans with atherosclerosis, diabetes, or hypertension often show impaired NO pathways. [50] Nitric oxide (NO) is a mediator of vasodilation in blood vessels.
Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). [1] This also refers to the condition of damage or rupture of small blood vessels. The best known and most prevalent angiopathy is diabetic angiopathy, a common complication of chronic diabetes.
The mean age at presentation is thirty-seven years with a reported range of nineteen to sixty-four years. The mean age of onset since diagnosis of diabetes is fifteen years. The female:male ratio is 1.3:1. Other diabetic complications such as nephropathy, neuropathy, retinopathy and hypertension are usually present. Its major symptom is the ...