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  2. Digestive enzyme - Wikipedia

    en.wikipedia.org/wiki/Digestive_enzyme

    The stomach plays a major role in digestion, both in a mechanical sense by mixing and crushing the food, and also in an enzymatic sense, by digesting it. The following are enzymes produced by the stomach and their respective function: Pepsin is the main gastric enzyme. It is produced in the stomach by gastric chief cells in its inactive form ...

  3. Gastrointestinal physiology - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_physiology

    Some of these enzymes are secreted by accessory digestive organs, while others are secreted by the epithelial cells of the stomach and intestine. While some of these enzymes remain embedded in the wall of the GI tract, others are secreted in an inactive proenzyme form. [4] When these proenzymes reach the lumen of the tract, a factor specific to ...

  4. Human digestive system - Wikipedia

    en.wikipedia.org/wiki/Human_digestive_system

    Pepsinogen is a precursor enzyme produced by the gastric chief cells, and gastric acid activates this to the enzyme pepsin which begins the digestion of proteins. As these two chemicals would damage the stomach wall, mucus is secreted by innumerable gastric glands in the stomach, to provide a slimy protective layer against the damaging effects ...

  5. Gastrointestinal wall - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_wall

    Goblet cells secrete mucus, which lubricates the passage of food along and protects the intestinal wall from digestive enzymes. In the small intestine, villi are folds of the mucosa that increase the surface area of the intestine.

  6. Gastric glands - Wikipedia

    en.wikipedia.org/wiki/Gastric_glands

    The gastric mucosa is covered in surface mucous cells that produce the mucus necessary to protect the stomach's epithelial lining from gastric acid secreted by parietal cells in the glands, and from pepsin, a secreted digestive enzyme. Surface mucous cells follow the indentations and partly line the gastric pits.

  7. Stomach - Wikipedia

    en.wikipedia.org/wiki/Stomach

    The stomach is surrounded by parasympathetic (inhibitor) and sympathetic (stimulant) plexuses (networks of blood vessels and nerves in the anterior gastric, posterior, superior and inferior, celiac and myenteric), which regulate both the secretory activity of the stomach and the motor (motion) activity of its muscles. The stomach is distensible ...

  8. Digestion - Wikipedia

    en.wikipedia.org/wiki/Digestion

    In mammals, preparation for digestion begins with the cephalic phase in which saliva is produced in the mouth and digestive enzymes are produced in the stomach. Mechanical and chemical digestion begin in the mouth where food is chewed, and mixed with saliva to begin enzymatic processing of starches. The stomach continues to break food down ...

  9. Gastrin - Wikipedia

    en.wikipedia.org/wiki/Gastrin

    Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach.It is secreted into the bloodstream. The encoded polypeptide is preprogastrin, which is cleaved by enzymes in posttranslational modification to produce progastrin (an intermediate, inactive precursor) and then gastrin in various forms, primarily the following three: