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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
[1] [3] [4] Its use in medicine has become less frequent, as safer and more effective products have become available. [5] Nitrofurazone is listed under California Prop 65 , and has demonstrated clear evidence to be mutagenic and carcinogenic during animal studies, and has been discontinued for human use in the USA.
In studies of dogs, the majority of urinary excretion is through glomerular filtration with some tubular secretion. [54] There is also tubular absorption which is increased with urine acidification. [54] However the activity of nitrofurantoin is also pH dependent and mean inhibitory concentration rises sharply with increased pH above 6. [54]
PetMed Express is an online pharmacy that sells prescription and non-prescription pet medication and nutritional supplements. [3] [4] It can only fill prescriptions written by veterinarians, and competes with veterinarians who derive some of their income from selling pet medication.
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A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]